You can use \begin{split} and \end{split} inside the equation. Use the ampersand character &, to set the points where the equations are vertically aligned.
\begin{equation}
\begin{split}
A & = \frac{\pi r^2}{2} \\
B & = \frac{1}{2} \pi r^2
\end{split}
\end{equation}
You can also put your equations inside \begin{align} and \end{align} to align them vertically.
\begin{align*}
x - 4y &= 18 \\
2x + 7y &= -22
\end{align*}